Zeto's wireless EEG machine

Expanding Global EEG Access: Zeto Research Program Supports Feasibility Study in Zambia

At Zeto, we’re committed to advancing EEG research and expanding access to brain monitoring technology worldwide. Through our annual Clinical Trial Sponsorship Program, we support researchers who are pushing the boundaries of neuroscience and patient care.

We’re proud to spotlight one of our 2025 winners: a groundbreaking feasibility study that could transform neurological care in sub-Saharan Africa.

Pilot Evaluation of Continuous EEG Implementation for Seizure and Status Epilepticus Management in Zambia (PRECISE-Z)

Led by Dr. Clio Rubinos and an international team of neurocritical care and epilepsy experts from the University of North Carolina (UNC) and University Teaching Hospital (UTH) in Lusaka, Zambia, this project seeks to evaluate the feasibility and acceptability of implementing continuous EEG (cEEG) using the Zeto One system in a low-resource healthcare setting.

Addressing a Critical Gap in Neurological Care

Over the past two decades, the use of continuous EEG (cEEG) monitoring has become an essential part of managing critically ill patients in high-income countries, particularly for detecting electrographic seizures (ESz) and electrographic status epilepticus (ESE). However, in low- and middle-income countries (LMICs), access to this life-saving technology remains extremely limited.

In Zambia, patients with altered mental status or coma rarely have access to cEEG, leading to undiagnosed seizures and potentially preventable neurological injury. The PRECISE-Z study aims to bridge this gap by introducing a rapid, full montage, wireless, and easy-to-use EEG solution that can be implemented without the infrastructure traditionally required for EEG monitoring.

Study Objectives

The trial has three key objectives:

  1. Feasibility: Evaluate the use of the Zeto One system for continuous EEG (cEEG) monitoring to detect ESz and ESE in adult patients with altered mental status or coma in Zambia.
  2. Acceptability: Assess perceptions of cEEG monitoring among patients, caregivers, nurses, and physicians in the Zambian clinical context.
  3. Prediction Modeling: Develop a clinical prediction score to identify patients at highest risk for ESz and ESE, optimizing cEEG use where resources are limited.

Study Design and Methodology

The study will take place at University Teaching Hospital (UTH) in Lusaka — Zambia’s national referral center — where the neurology team has established EEG interpretation expertise.

The research team will recruit adult patients (≥18 years) with Glasgow Coma Scale ≤11 or FOUR score ≤12, who are being treated in either internal medicine wards or the ICU. Participants will undergo a 24-hour cEEG recording using the Zeto One device, with data interpreted by epileptologists in Zambia and the United States.

If seizures or status epilepticus are detected, the clinical care team will be notified for management per standard local protocols.

To assess feasibility, the team will document recording quality, artifact levels, and any operational challenges such as WiFi disruptions, power outages, or electrode displacement. Implementation feedback will also be gathered from the Zambian care teams and EEG technicians trained to use the system.

Acceptability will be evaluated through surveys and in-depth interviews with patients, caregivers, and healthcare providers, recognizing that epilepsy remains a highly stigmatized condition in Zambia and that patients are often cared for in open wards.

Building Local Capacity and Contextual Solutions

Beyond feasibility, the PRECISE-Z team will train neurology residents and EEG technicians on how to use the Zeto EEG system,  fostering local expertise and long-term sustainability.

Importantly, the project aims to create a clinical prediction score tailored to Zambia’s patient population, helping clinicians identify those most likely to benefit from cEEG monitoring. This data-driven approach could guide future clinical decision-making in resource-limited settings.

Multidisciplinary Collaboration

The PRECISE-Z study is led by a collaborative team that brings together extensive experience in neurocritical care, EEG research, and global health:

  • Principal Investigator: Dr. Clio Rubinos, a neuro-intensivist and neurophysiologist from UNC with experience in ICU cEEG implementation in resource-limited environments.
  • Dr. Deanna Saylor, neurologist and clinical researcher at UTH and leader of Zambia’s neurology training program.
  • Dr. Melody Asukile, Zambia’s first epileptologist and a recipient of a Royal Society of Tropical Medicine and Hygiene grant.
  • Dr. Suzette LaRoche, epileptologist and advocate for improving neurodiagnostic access in underserved communities.

Ethical Oversight and Funding

The project will obtain ethical clearance from both the UNC Institutional Review Board and the University of Zambia Biomedical Research Ethics Committee. Informed consent will be obtained from participants or their legal representatives.

Funding for the cEEG recordings will be supported by the Zeto Research Program, with additional grant applications submitted to the Neurocritical Care Society Research Training Grant and INCLINE (Investing in CLINical Neurocritical CarE Research) Grant programs.

Anticipated Impact

The PRECISE-Z study is expected to demonstrate that rapid, wireless EEG can be feasibly and acceptably deployed in Zambia’s healthcare environment, despite infrastructure challenges such as limited ICU capacity, variable power supply, and the need for culturally sensitive implementation.

By developing local workflows, training healthcare professionals, and generating data to identify high-risk patients, the study represents a major step toward making continuous EEG accessible in resource-limited settings.

About the Zeto EEG Clinical Trial Sponsorship Program

Zeto EEG Clinical Trial Sponsorship program supports investigator-led projects that explore new frontiers in EEG access, usability, and clinical impact. Through partnerships with researchers and institutions around the world, Zeto aims to advance the understanding of brain health and make EEG monitoring more accessible to patients everywhere

More details: link

Zeto Selects Clinical Trial Sponsorship Recipients Advancing EEG in Critical Care, Stroke, and Concussion Research

Santa Clara, CA – July 29, 2025 – Zeto, Inc., a fast-growing medical technology company revolutionizing EEG diagnostics with its cutting-edge devices and cloud platform, is proud to announce the latest recipients of its 2024–2025 Clinical Trial Sponsorship Program.

The program supports the use of EEG in real-world healthcare and clinical research applications by providing teams with access to Zeto’s innovative, rapid-setup, gel-free EEG solution.

“The selected projects reflect the diverse and expanding role of EEG in improving patient outcomes across settings,” said Zoltan Nadasdy, Ph.D., Principal Neuroscientist at Zeto. “From concussion studies in athletes to seizure detection in low-resource ICUs, these projects reflect the power of EEG to transform patient care globally – and the flexibility of Zeto to make it possible.”

The winners are:

Pilot Evaluation of Continuous EEG Implementation for Seizure and Status Epilepticus Management in Zambia (PRECISE-Z) by Clio Rubinos, MD, University of North Carolina

This trial aims to implement continuous EEG (cEEG) monitoring for critically ill patients with altered mental status in Zambia, evaluating its feasibility and acceptability in a resource-limited setting. It also seeks to develop a clinical prediction score to identify patients at highest risk for electrographic seizures and status epilepticus. As one of the first studies exploring cEEG in a lower- to middle-income inpatient setting, it will lay crucial groundwork for improving neurocritical care and reducing disparities in global neurological outcomes.

Optimizing emergency stroke transport strategies using EEG-based biomarkers and machine learning by F. Samuel Racz, MD, University of Texas at Austin

This project aims to improve emergency stroke care by developing a machine learning-based tool that uses EEG recordings to distinguish large vessel occlusion strokes from other conditions with similar early symptoms – before the patient arrives at the hospital. By enabling real-time assessment in the ambulance, this system could help guide whether a patient needs to be transported to the nearest emergency room or instead an endovascular thrombectomy-capable center. If validated, the approach could support future efforts to streamline and optimize stroke triage protocols and reduce treatment delays.

Contribution of Resting and Dynamic Electroencephalogram (EEG) to Assess Athletes Before and After Acute Concussion by Maria Martinez, Ph.D,, University of São Paulo, Brazil

This research will use EEG to evaluate brain activity changes in athletes before and after acute concussion, supporting improved assessment and return-to-play decisions.

Each project will receive Zeto ONE EEG headsets, access to Zeto’s cloud platform, and electrode kits for participants. Trials are expected to begin later this year. 

About Zeto, Inc.

Zeto, Inc., is an award-winning, privately held medical technology company located in Santa Clara, CA, focused on transforming the way electroencephalography is done in clinical and research settings. 

The company plans to leverage its platform technology to improve access and quality to medical EEG testing and to enable and improve adjacent biomedical research and clinical trials. Zeto’s EEG systems, which received FDA clearances in 2018 and 2024, are currently commercially available in the United States.

To learn more about Zeto’s products, please visit https://zeto-inc.com/ or email us at research@zetoinc.com.

Source: Newswise

Zeto ONE Billing: Expanded CPT Codes for 24+ Hour EEG Monitoring

Full-Montage EEG with video capabilities

Understanding the appropriate CPT codes for EEG services is essential for accurate billing and reimbursement. With the introduction of Zeto ONE, our latest EEG headset for continuous monitoring, Zeto now has a product that can support both routine and longer-duration EEG studies. Following proper billing practices, Zeto now aligns with the expanded set of EEG CPT codes to support accurate documentation and billing.

In addition to our WR19 system for routine EEG collection, Zeto ONE enables extended monitoring up to 24+ hours with video, enabling clinicians to perform longer studies that may align with long-term EEG CPT codes.

Please note: The information provided in this article is for educational purposes only. This content is not intended as billing, coding, reimbursement or financial advice. Healthcare providers are advised to consult legal counsel and billing and coding specialists to determine appropriate CPT codes based on specific procedures, payer requirements, and patient needs.

Introducing Zeto ONE

Zeto ONE is our latest advancement in EEG monitoring, designed for long-term, continuous EEG monitoring in acute care settings. Zeto ONE is a user-friendly full-montage headset and a portable recording device that provides reliable bedside seizure detection*, accompanied by video, audio, and live remote monitoring and interpretation service. 

* enabled by encevis

WR19 vs. Zeto ONE: Enhanced Capabilities

Note: The devices shown in this comparison image are for illustrative purposes only. In clinical practice, the Display Unit (DU) is mounted on bedside stands, not held by patients during monitoring.
WR19Zeto ONE
Monitoring DurationUp to 6 hours24+ hours
Primary Use CasesRoutine EEGTriage, Routine, Stat, and Continuous EEG
Video IntegrationYesYes
Billing Codes RangeRoutine EEG codesFull spectrum including extended monitoring

Expanded CPT Code Coverage with Zeto ONE

For standard routine EEG billing codes (studies up to 2 hours), refer to our blog: Billing for Zeto: Zeto EEG Billing CPT Codes.

Long-Term Video EEG Monitoring (2-12 Hours)

VideoMonitoringCPT Code Technical ComponentCPT Code Professional Component
Without VideoUnmonitored9570595717
Without VideoIntermittent9570695717
Without VideoContinuous9570795717
With VideoUnmonitored9571195718
With VideoIntermittent9571295718
With VideoContinuous9571395718

Professional component codes include 95717 for studies without video and 95718 for studies with video. Zeto ONE’s advanced multi-stream video capability enables providers to utilize the video EEG codes when clinically appropriate.

Long-Term Video EEG Monitoring (12-26 Hours)

VideoMonitoringCPT Code Technical ComponentCPT Code Professional Component
Without VideoUnmonitored9570895719
Without VideoIntermittent9570995719
Without VideoContinuous9571095719
With VideoUnmonitored9571495720
With VideoIntermittent9571595720
With VideoContinuous9571695720

Technical Component for 24-Hour Monitoring

Technical component billing includes several options for extended monitoring:

  • 95950 for seizure-focused monitoring for each 24-hour period, 95951 covers each additional 24-hour period. 
  • 95953 applies to computerized portable 16+ channel EEG monitoring for each 24-hour period
  • 95956 covers portable EEG monitoring for each 24-hour period.

Video EEG: Enhanced Clinical Value and Reimbursement

Zeto ONE’s multi-stream video capability captures patient behavior, environmental factors, and seizure activity, enabling complete clinical assessment during long-duration EEG recordings. These integrated capabilities are designed to support robust documentation and assist clinicians in demonstrating medical necessity during the payer review process.

Key Documentation Requirements

Successful reimbursement for extended monitoring requires thorough documentation of medical necessity for monitoring durations exceeding routine timeframes. Clinical indications must clearly support the need for continuous versus intermittent monitoring EEG recordings. When billing video EEG codes, documentation should include specific rationale for video recording as well as the duration of the EEG based on clinical presentation and diagnostic requirements.

For 24+ hour studies, seizure detection protocols and safety monitoring procedures should be clearly documented to support medical necessity and appropriate code selection.

Conclusion

Healthcare providers can utilize Zeto ONE’s comprehensive monitoring range, from routine diagnostic studies to extended seizure monitoring with synchronized video capture.

For individualized guidance on EEG billing, several third-party consulting service providers are active in the market. For questions or an introduction to a consultant familiar with Zeto, complete the form below.


    Disclaimer

    Zeto, Inc. does not provide billing or coding services and does not offer advice, guidance, or recommendations regarding billing, coding, reimbursement, or claims submission. The information presented in this article is intended solely for general informational purposes and should not be construed as legal, compliance, coding, reimbursement, or financial advice.

    It is the sole responsibility of each individual or organization to ensure the accurate selection and application of codes, modifiers, coverage, and documentation, as well as to establish medical necessity and submit claims in full compliance with all applicable federal, state, and local laws, regulations, and payor policies, including those of Medicare, Medicaid, and commercial insurers. To mitigate potential legal, financial, or regulatory risks, it is strongly recommended to consult with qualified legal counsel and experienced coding or reimbursement professionals. Requirements should also be independently verified with relevant payers and authoritative sources, prior to making any billing or coding decisions. This article is not a substitute for professional guidance or independent verification.

    Zeto, Inc. makes no representations or warranties regarding the accuracy, completeness, or applicability of the information provided and expressly disclaims any liability for any losses, damages, or other consequences that may result from reliance on this content. Use of this information is at your own risk.

    EEG in Supine Position: Making Bedside Monitoring Truly Bedside

    Zeto ONE enables rapid, full-montage EEG while patients remain comfortably lying down – no gels, no electrode wires, no repositioning. ICU and ED teams now have a solution that matches the pace and complexity of real-world care.

    Why Supine EEG Access Matters in Critical Care

    In critical care and emergency environments, most patients are not sitting up. They’re post-surgical, unconscious, intubated, or in a medically complex state that makes repositioning impossible.

    Being able to conduct high-quality EEG while lying down is more than a convenience. It’s a matter of life-saving speed.

    Zeto ONE: Built for the Bedside

    In most hospitals today, traditional EEG is still the standard of care – but that doesn’t mean it’s easy. These systems offer the full-montage data neurologists rely on, but they come with significant logistical hurdles. Setup takes 20–30 minutes, requires a trained EEG technologist, involves abrasive skin prep, messy gels, and a maze of wires. Especially for patients in critical conditions, with limited ability for re-positioning, preparing the scalp and gluing down traditional gel-based electrodes can take even longer than usual. 

    In response to these challenges, a new category of “rapid EEG” systems has emerged. But while these devices promise speed, they often sacrifice quality. Unlike some rapid EEG systems that are bulky or uncomfortable for patients lying down, the Zeto ONE is designed with a low-profile form that makes it easy for patients to rest comfortably on a pillow—no neck towel or special positioning required. The headset can be applied in under five minutes and removed just as quickly if a CT or MRI is needed. It’s gel-free and paste-free, so there’s no mess to clean up, and unlike many limited-channel systems, Zeto ONE delivers a full-montage 21-channel EEG, giving clinicians the diagnostic quality they need without compromising patient comfort.

    Remote EEG Monitoring Without Compromise

    Zeto ONE is more than just a rapid setup. It also supports real-time, cloud-based EEG streaming and integrates AI-powered seizure detection. Zeto comes closest to a traditional full montage EEG with all its benefits and seamless integration with the cloud.

    Here’s what that means in the field:

    • Remote neurologists can begin interpreting EEG as soon as the recording starts.
    • The system provides automatic notifications for seizure activity and status epilepticus.

    That means faster intervention. More accurate diagnosis. And fewer unnecessary patient transfers.

    What Makes It Different From Traditional EEG?

    FeatureTraditional EEGZeto ONE
    Patient Comfort Gel dries, wires interfereSleek design makes it comfortable.  
    Setup Time15–25 minutes  ~ 5 minutes
    Specialized Technologist RequiredYesNo – any trained staff member
    Gel / Paste RequiredYesNo
    Patient Clean-up RequiredYesNo

    Zeto ONE has been used to record over clinical 150,000 EEGs, many of them in high-stakes emergency and ICU environments. Providers using the system report faster workflows, better patient experiences, and a major reduction in unnecessary transports.

    Ready to See It in Action?

    Request a demo of Zeto ONE and learn how you can implement rapid, full-montage EEG at the bedside, in the ICU, or anywhere care happens.

    EEG for Nurses: A Rapid Full EEG When Every Minute Counts

    Zeto ONE makes it possible for nursing staff to initiate high-quality EEGs—no gel, no wires—when EEG technologists are unavailable.

    In many hospitals, especially in emergency departments, intensive care units, and rural facilities, nurses are often the first clinicians to respond when a patient shows signs of a neurological emergency—such as nonconvulsive seizures, status epilepticus, or post–cardiac arrest encephalopathy. But traditional EEG systems are generally not deployed by nurses. They require EEG technicians – critical practitioners who unfortunately may not be always available in rural settings or off-hours. 

    Zeto ONE offer Rapid FULL Montage EEG for the ICU

    It is the first FDA-cleared, full-montage EEG system that can be applied by trained nursing staff when EEG techs are unavailable—without requiring gels, glues, or specialized tools. The system is intuitive and wireless, enabling clinicians to initiate EEGs within minutes, even in critical care environments.

    EEG technologists remain the gold standard in the administration of EEG studies. Zeto ONE offers EEG techs, and when they’re not available, other front-line staff such as nurses, an invaluable and easy to use tool when time to treatment is critical, and expert personnel are not immediately on-site.

    Why Fast EEG Access Matters

    EEG plays a vital role in diagnosing seizures—especially nonconvulsive seizures and nonconvulsive status epilepticus, which can be difficult to identify through clinical observation alone. In neurocritical care and emergency medical settings, delayed EEG access can delay treatment, particularly for patients in altered mental states following epileptic seizures or cardiac arrest.

    Traditional EEG systems require:

    • Specialized EEG technologists for setup and monitoring
    • 15–20 minutes or more for electrode placement
    • Gels, wires, and post-procedure cleanup

    In the absence of an EEG tech, clinicians must either wait until they are available, which could be days, or transfer the patient— a time-intensive and resource-draining process.

    With Zeto ONE, trained nurses can initiate EEGs in under five minutes, helping reduce diagnostic delays and supporting earlier intervention.

    Zeto ONE: A Nurse-Friendly EEG System, Not a Replacement for Technologists

    Zeto ONE is user-friendly enough to be deployed by neuro-ICU nurses, emergency teams, or critical care staff with minimal training. When EEG techs are unavailable, it enables immediate EEG acquisition that can be reviewed by physicians or EEG personnel remotely.

    Key features include:

    • Full-montage high-quality EEG
    • Application in under 5 minutes—no gels, wires, or prep
    • Comfortable for supine patients in ICUs or emergency bays
    • Portable, compact headset fits seamlessly into crowded units
    • Quick to remove and reapply

    Once applied, Zeto ONE begins recording immediately, sending data to a secure cloud-based platform that enables remote access for neurologists and EEG staff for interpretation.

    Built-In Seizure Detection with NeuroPulse AI™

    Zeto ONE includes NeuroPulse AI™, an AI-powered seizure detection tool trained on more than 21,000 hours of EEG recordings across over 800 patients. It continuously monitors for abnormal brain activity and automatically alerts care teams.

    If seizure activity is detected:

    • Nurses receive a notification at the bedside
    • Physicians and EEG techs can be notified remotely

    This capability empowers nursing staff to identify and respond to neurological deterioration, even in the absence of on-site specialists.

    Streamlining Workflow for Nurses in Critical Care

    Zeto ONE is designed to work within the constraints of busy, high-acuity units:

    • EEG studies are immediately available to remote neurologists
    • NeuroPulse AI™ generates real-time summaries and insights
    • No need to transport patients only to get EEG or coordinate external EEG services

    It’s especially valuable during night shifts, weekends, or in smaller facilities without 24/7 neurology or EEG coverage.

    Additionally, the system is:

    • Quick to remove and reapply for imaging procedures
    • Compact enough to store and charge within neurocritical care units
    • Non-disruptive to existing care protocols

    Easy to Clean: A 5-Minute Protocol 

    Zeto ONE is also easy to maintain, with cleaning protocols that meet infection control standards without consuming staff time.

    Our happy customer at Huntsville Memorial Hospital (HMH) in Texas, shared with us that their staff follow a 5-minute cleaning process that has passed routine inspections by their infection control nurse.

    The process:

    • Step 1: Remove the headset—no gel, no residue, no skin irritation
    • Step 2: Wipe down the device using hospital-approved SaniWipes
    • Step 3: Use 70% isopropyl alcohol

    “Cleaning takes about five minutes. We use hospital-approved wipes to reach all areas. Infection control inspected and approved the process.”
    — Joe Schorre, Director of Cardiopulmonary and Emergency Management, HMH

    Additional notes:

    • Cleaning is performed by respiratory techs or nurses immediately after use
    • Devices are stored in designated, upright positions for charging and longevity

    The result is a workflow-friendly process that supports rapid turnover between patients.

    Conclusion: A Critical Tool for Emergency Gaps

    EEG techs are indispensable, and Zeto ONE is not a substitute for their expertise. But in moments when rapid neurological insight is needed—and a tech isn’t available—Zeto ONE gives nurses a fast, accessible solution.

    By empowering nurses to apply EEGs in urgent moments, Zeto ONE helps prevent treatment delays, reduce unnecessary transfers, and improve outcomes in emergency and intensive care settings.

    Want to see how Zeto ONE fits into your neurocritical care workflow?

    Schedule a demo or explore our quick-start training resources.

    Huntsville Memorial Hospital Reduces Patient Transfers and Enhances Local Care with Onsite EEG Program Powered by Zeto

    HUNTSVILLE, TX, June 11, 2025 / PRNewswire/ – Zeto, Inc. is proud to announce the success of a new onsite EEG program at Huntsville Memorial Hospital (HMH) that has helped reduce emergency room patient transfers and improve access to neurological diagnostics for the Huntsville community and surrounding areas. As the only hospital within a 30-mile radius, HMH now offers critical services that previously required transfers to larger facilities in Conroe, The Woodlands, or Houston.

    An EEG (electroencephalogram) is a test that measures electrical activity in the brain and is commonly used to diagnose seizures, stroke, and other neurological conditions.

    Faced with a high volume of neuro-related transfers and limited access to specialty care, HMH leadership assembled a task force to study ER transfer patterns. “We looked at two years of transfer data and saw that many patients were being transferred for neuro-related issues, particularly when an EEG was needed,” said Joe Schorre, Director of Cardiopulmonary and Emergency Management, who led the EEG implementation at HMH. “Our goal was to turn those transfers into local admissions.”

    Knowing that the EEG services were needed for Huntsville and Walker County, the hospital explored options for bringing neurological diagnostics in-house as part of a broader inpatient teleneurology and stroke program. The result was the successful implementation of a rapid EEG solution from Zeto that requires no gels or pastes and can be set up by respiratory therapists in under five minutes. “We’re not EEG techs, so we needed a solution that was easy to learn, easy to apply, and could integrate with remote neurologists for interpretation,” said Schorre.

    Since the program’s launch in December 2024, HMH has been able to admit more than 40 patients who would otherwise have been transferred to a facility over 30 miles away at a minimum. “Having the ability to implement an EEG program here at HMH is huge step forward for us to elevate the level of care for Walker County residents. Receiving high quality services closer to home which means families and loved ones don’t have to travel, lose time from work, or worry about being separated from loved ones during treatment,” Patrick Shannon, CEO of HMH stated. “For many in our rural community, that makes a huge difference.”

    The program has also supported the development of an outpatient EEG program, allowing local primary care providers to refer patients for pre-neurology diagnostic testing. “We’re helping patients get their EEG and MRI here, so by the time they go to the neurologist, they have data in hand,” said Schorre. “It shortens the wait time and gets them the care they need faster.”

    Looking ahead, HMH plans to expand services into continuous EEG monitoring and outpatient teleneurology. “This is about doing what’s right for our community. We don’t have local neurology, but we do have smart, committed staff and the tools to support them,” said Schorre.

    About Huntsville Memorial Hospital
    Huntsville Memorial Hospital, Huntsville, Texas, is currently a 123-bed, CIHQ‐accredited, not‐for‐profit acute care community hospital. HMH delivers quality healthcare services to the residents of Walker County and its surrounding communities, a population of more than 82,000. HMH and its dedicated staff offer compassionate care and the latest technologies and treatment solutions. HMH holds the American Heart Association Primary Stroke Center designation. HMH keeps community health and wellness at the forefront of its mission. Please visit us at www.huntsvillememorial.com.

    Source: PRNewswire

    Zeto, Inc. joins Innovators’ Network at American Heart Association Center for Health Technology & Innovation

    American Heart Association consortium advances development of evidence-based health tech solutions

    SANTA CLARA, Calif., May 29, 2025 /PRNewswire/ – Zeto, Inc., a fast-growing medical technology company revolutionizing EEG diagnostics with its cutting-edge devices and advanced cloud platform, has joined the American Heart Association Center for Health Technology & Innovation’s (the Center) Innovators’ Network. The Center is focused on building and fostering health technology relationships to develop innovative and scalable solutions. 

    The Innovators’ Network is a consortium connecting entrepreneurs, providers, researchers and payers to advance cardiovascular and brain health innovation. Innovators’ Network members also have the opportunity to access the Association’s digital evidence-based scientific guidelines and clinical recommendations as they develop digital healthcare technologies. Members interact with the Center in different ways, including building models for clinical outcome studies, which lowers the significant cost of developing those studies independently, helping connect the science to technology and providing evidence that a digital platform improves healthcare outcomes – a key concern for providers and payers.

    “The Center aims to advance the rapid, efficient and effective development of healthcare technology,” said Robert A. Harrington, M.D., FAHA, said Robert A. Harrington, M.D., FAHA, volunteer past president of the American Heart Association (2019-2020), chair of the American Heart Association’s Health Tech Advisory Group for the Center and the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine and provost for medical affairs of Cornell University. “Joining the Innovators’ Network gives members the opportunity to leverage the consortium and work toward broadening and deepening their engagement in this arena.”

    “We’re happy to join the American Heart Association’s Innovators’ Network to advance scalable, evidence-based solutions in neurology,” said Aswin Gunasekar, Founder and CEO of Zeto, Inc. “At Zeto, we strive to bridge clinical needs with technology that’s both accessible and impactful. We’re excited to join the Center to drive meaningful innovation in brain monitoring and improve outcomes in critical care and beyond.”

    Non-convulsive status epilepticus (prolonged seizures) is a major neuro-emergency in acute care, with up to 1 in 3 neurological ICU patients at risk for seizures that can lead to brain injury or death. To help address this challenge, Zeto offers rapid, full-montage EEG with AI-powered status epilepticus and seizure detection — enabling timely, bedside diagnosis and intervention when it matters most.
    1 Seizure Management in the Intensive Care Unit – PMC

    About Zeto, Inc.

    Zeto, Inc., an award-winning medical technology company, is at the forefront of advancing EEG brain monitoring and diagnostics in healthcare. Through its innovative wearable devices, Zeto makes brain monitoring accessible in diverse clinical settings, including the ICU, ED, hospitals, offices, and at home. Backed by a powerful cloud-based platform, Zeto delivers nationwide monitoring and interpretation services by neurologists, along with AI-powered notifications for conditions such as seizures and epilepsy. Looking ahead, Zeto plans to expand its capabilities to detect and manage conditions like stroke and traumatic brain injury. Zeto’s EEG systems, which received FDA clearances in 2018 and 2024, are currently commercially available in the United States.

    To learn more about Zeto’s products, please visit: https://zeto-inc.com or email us at info@zetoinc.com.

    Source: Newswise

    Zeto Unveils NeuroPulse, the First AI-Powered Status Epilepticus Software Using Full 10-20 EEG in Collaboration with encevis*

    SANTA CLARA, Calif., April 2, 2025 /PRNewswire/ — Zeto, Inc., a fast-growing medical technology company revolutionizing EEG diagnostics with its cutting-edge devices and advanced cloud platform, announces the integration of live bedside AI-powered Seizure Burden and Status Epilepticus detection. Utilizing encevis, a leading FDA-cleared EEG analysis software developed by the Austrian Institute of Technology, this new capability enhances EEG monitoring with automated detection and notifications for Status Epilepticus—a life-threatening, prolonged seizure condition requiring immediate intervention.

    Up to one-third of neurological critical care and emergency department patients are at risk for seizures, which can lead to permanent brain injury and increased mortality risk1. Access to timely EEG interpretation remains an unmet need, particularly in emergency and critical care settings, where rapid and reliable medical intervention is essential.2

    “Our product development has been guided by neurologists, critical and emergency care physicians who sought rapid, clinical-grade EEG with full-head coverage and video to not miss clinically relevant events3. They emphasized the need for accurate bedside seizure detection that enables real-time review and validation by neurologists, ensuring patients receive timely and appropriate treatment,” said Aswin Gunasekar, Founder and CEO of Zeto, Inc. “We introduced the Zeto ONE, a best-in-class, full 10-20 EEG system offering rapid setup, video, and remote reading services—being fast embraced by U.S. hospitals. With the addition of AI-powered seizure detection, we now offer a comprehensive, all-in-one solution that significantly enhances neurocritical assessment.”

    encevis utilizes a cutting-edge AI model to detect seizures, seizure burden, and electrographic status epilepticus. Trained on a diverse dataset of over 21,400 hours of EEG recordings from more than 800 patients, the model was further validated using an independent dataset from 81 patients. Expert reviewers from top U.S. and European institutions meticulously labeled the data, ensuring highly accurate and clinically meaningful insights.

    “We are delighted to continue our successful partnership with Zeto,” said Dr. Tilmann Kluge, Head of Medical Signal Analysis at AIT Austrian Institute of Technology. “Our algorithms allow physicians to detect seizure burden and electrographic status epilepticus early and with high sensitivity without the need for continuous expert monitoring of the EEG. Our EEG analysis software has been utilized by leading hospitals for over a decade, with capabilities such as artifact reduction, spike and seizure detection with high sensitivity and specificity.”

    Zeto’s full 10-20 EEG platform now features AI-powered seizure burden detection with advanced EEG analysis tools providing comprehensive clinical value for ICU Monitoring as required by ACNS, the American Clinical Neurophysiology Society. Supported by nationwide neurologist reading services, hospitals can expand EEG access without additional infrastructure. More healthcare providers are adopting rapid EEG-powered diagnostics, enabling timely, life-saving decisions.

    To learn more about how Zeto’s solutions can be integrated into your hospital, contact us at sales@zetoinc.com.

    * The encevis Component for Detection of Seizures and Electrographic Status Epilepticus is indicated for the detection of Seizures and Electrographic Status Epilepticus in patients greater than or equal to 18 years of age who are at risk for seizures.

    About Zeto, Inc.

    Zeto, Inc., an award-winning medical technology company, is at the forefront of advancing EEG brain monitoring and diagnostics in healthcare. Through its innovative wearable devices, Zeto makes brain monitoring accessible in diverse clinical settings, including the ICU, ED, hospitals, offices, and at home. Backed by a powerful cloud-based platform, Zeto delivers nationwide monitoring and interpretation services by neurologists, along with AI-driven notifications for conditions such as seizures and epilepsy. Looking ahead, Zeto plans to expand its capabilities to detect and manage conditions like depression, stroke and traumatic brain injury. Zeto’s EEG systems, which received FDA clearances in 2018 and 2024, are currently commercially available in the United States.

    To learn more about Zeto’s products, please visit: https://zeto-inc.com or email us at info@zetoinc.com.

    About Medical Signal Analysis at AIT (Austrian Institute of Technology)

    Medical Signal Analysis at AIT is dedicated to the development of powerful algorithm and medical software solutions for the analysis of neurophysiological data. As part of the Austrian Institute of Technology, Austria’s largest non-university research institute, the team of researchers and software professionals developed the CE certified and FDA cleared EEG analysis software suite ‘encevis‘ which is included in EEG platforms in Europe and the US The algorithms and software for Zeto, Inc., are the most recent developments.

    1 Kozak, R., et al. (2023). JACEP Open. 4(4)
    2 Herman, S.T., et al. (2015) J Clin Neurophysiol. 32(2):87-95
    3 Rubin MN, et al. Neurohospitalist (2014) PMID: 24381704; PMCID: PMC3869310

    Source – PRNewswire

    EEG in Healthcare Transformed: Zeto Makes EEG Accessible Everywhere

    While EEG in healthcare is the main use of the technology, EEG is no longer confined to hospital rooms. With Zeto’s cutting-edge technology, brain monitoring has become accessible in places you wouldn’t expect. From concert halls to ambulances, our portable, gel-free EEG systems empower researchers, clinicians, healthcare providers and caregivers to rethink where and how EEG can be used to improve lives.

    At Zeto, we’re driving a new era of accessibility in EEG, transforming patient care and expanding its reach beyond traditional settings. In this blog, we explore real-world examples of how portable EEG is making an impact in diverse environments.

    Join us in discovering how brain monitoring is becoming a seamless part of everyday life.

    Bring EEG to ICUs and EDs

    Our latest innovation, ONE, is making emergency EEG faster and easier, especially for hospitals that don’t have dedicated EEG resources. With full 10-20 electrode placement, video and audio recording, AI-powered triage tools, seizure activity monitoring, and remote reading services, ONE brings real-time brain monitoring right to the bedside.

    Huntsville Memorial Hospital successfully implemented ONE for bedside brain monitoring, enabling nurses to apply the EEG headset in just about 5 minutes. The system provides real-time notifications for patients with suspected non-convulsive seizures, supporting faster and more informed clinical decisions around brain function.

    Why It Matters:

    In emergency settings, every second counts. Traditional EEG systems often require specialists and lengthy setups, delaying critical care. Zeto changes that.

    Key Benefits

    • Eliminates the need for costly and time-consuming patient transfers to larger hospitals.
    • EEG setup can be performed by non-EEG technicians.
    • Rapid data collection decreases the period of time it takes to get faster diagnosis and intervention.
    Zeto-ICU

    EEG is Everywhere: Even Rural Hospitals

    EEG in healthcare can be found in services in rural hospitals across the U.S. are often limited due to a shortage of trained EEG technologists and neurologists.

    Zeto addresses this challenge by enabling any healthcare provider or member of the medical staff to initiate EEG when needed, with seamless access to remote EEG reading services through our cloud platform.

    Greenwood Leflore Hospital, a small community hospital in Greenwood, Mississippi, has been using Zeto EEG for routine EEGs. One of the key benefits they have noted is the significantly faster turnaround time for reading and interpreting EEG tests, with results now available the same day.

    Zeto at GLH-2023

    Why It Matters:

    Patients in remote areas often face long commutes for advanced neurological care. Zeto’s portable EEG bridges the gap by bringing diagnostics directly to them.

    Why are rural hospitals choosing Zeto EEG:

    • Expands access to advanced neurological care for rural patients in emergency (such as post brain injury) and non-emergency settings.
    • Reduces financial and logistical burdens associated with patient transfers.
    • Promotes healthcare equity by enabling local hospitals to provide specialized care.

    “The biggest challenge of getting EEGs done in small community hospitals is the lack of EEG technologists. This lack of EEG technicians incentivizes ordering physicians to just send patients to a metropolitan hospital for EEG testing.” – Steven Robinson, director of cardiopulmonary care, Greenwood Leflore Hospital.

    Bring EEG to Neurology Offices and Clinics

    Zeto is commonly used in neurology offices due to its ease of use, with many customers noting shorter wait times for testing and improved patient experience. Dr. Randy Baculi from RHB Neuro shared his experience:

    “In the short term, we quickly cleared a backlog of 100+ patients, including new ones, within just a few weeks. In the long term, the system’s ease of use means we’re no longer limited by the availability of specific staff members, ensuring essential diagnostics are completed on time..”

    Full story: Case Study: Zeto’s Modern EEG at RHBNeuro | ZETO

    Why It Matters:

    Outpatient EEG procedures are often delayed due to complex setups and staffing shortages. Zeto simplifies the process, making it feasible to conduct more EEGs in less time and on an outpatient basis.

    Key Benefits:

    • Gel-free headset for increased patient comfort.
    • Quick setup reduces appointment durations and increases throughput.
    • Can be operated by medical assistants, freeing neurologists for more critical tasks.

    Watch how RHB uses Zeto at its clinic:

    Bring EEG to Pediatric Neurology

    Children often find traditional EEGs in healthcare settings uncomfortable due to gel applications and restrictive equipment. Zeto’s design prioritizes comfort, making EEG sessions more child-friendly. Pediatric neurologists who implemented Zeto report that the setup is fast and easy.

    Key Benefits:

    • Gel-free electrodes eliminate the need for hair alterations.
    • Reliable data capture, even for active or restless children.
    • Faster setup reduces waiting times and anxiety.

    Read our interview with Dr. Christina M. Patterson, Director of Epilepsy and EEG Services at UPMC Children’s Hospital of Pittsburgh, on how her team incorporates Zeto into pediatric EEG care.

    Bring EEG to Ambulances

    There is currently no effective way to assess brain injuries or perform brain monitoring in an ambulatory environment. However, early diagnosis during transport can significantly improve patient outcomes. Zeto’s latest EEG system, ONE, enables emergency responders to begin neurological assessments to the ambulance or helicopter, on the way to the hospital.

    Key Benefits:

    • Portable EEG system can be used inside ambulances.
    • Provides high-quality data capture during transport.
    • Enables pre-hospital interventions that can save lives.

    FDA Cleared: ONE is FDA-cleared for use in both air and ground transport, setting a new standard for mobile neurological care.

    EEG in Concert Halls: The Music-in-Medicine Initiative at MD Anderson

    Zeto EEG has been used to study the neurological effects of music therapy on patient recovery and well-being. We see this study with the pioneering work of Dr. Mei Rui, Director of Music-in-Medicine at MD Anderson Cancer Center, who used Zeto EEG to explore how classical music influences brain recovery. She believed that by capturing brain waves and their activity during performances, clinicians can unlock new therapeutic pathways for a range of neurological conditions.

    Research has shown that music can significantly impact brain activity via neuroplasticity and emotional regulation. By bringing EEG into live music therapy sessions, researchers can better understand these neurological responses in real time.

    Why MD Anderson Chose Zeto’s EEG:

    • Portable, gel-free design makes for ease of use and wearing for unconventional settings like music halls.
    • Non-invasive, quick setup that doesn’t interfere with the therapy session and can be easily set up by any healthcare provider.
    • Real-time data collection on brain activity for more impactful research outcomes.

    Bring EEG to Research Labs – University of Rochester Medical Center

    EEG systems are employed in research to study neurological activity and electrical patterns in experimental settings. Dr. Ram Haddas, a  director of UR Medicine Motion Labs at the University of Rochester, shared how Zeto’s EEG enabled them to conduct more seamless studies on brainwave activity without subjecting participants to traditional EEG discomfort.

    Dr Ram Haddas

    Why It Matters:

    Research labs require reliable data without cumbersome setups. Zeto enables researchers to focus on their experiments rather than technical issues.

    Key Benefits:

    • High-quality, reliable data collection to support robust research.
    • Portable and easy-to-use system with no need for gel or extensive preparation.
    • Compatible with all hair types, ensuring inclusivity in participant recruitment.

    Click here to see Dr. Ram Haddas in action.

    Bring EEG to Neurofeedback Clinics

    Neurofeedback sessions often require multiple visits. A quick, comfortable EEG setup ensures patients can seamlessly fit sessions into their schedules.

    Key Benefits:

    • Gel-free, quick setup minimizes patient discomfort.
    • Portable design enables for frequent, non-disruptive sessions.
    • Perfect for lunch-break appointments.

    Bring EEG to Senior Living Communities

    Early detection of cognitive decline can improve quality of life for seniors. However, EEG tests can be uncomfortable for older adults. Zeto’s gentle design addresses this challenge.

    Zeto EEG Headset B9994282

    Key Benefits:

    • Soft-tipped electrodes are gentle on hair and scalp.
    • Quick setup without gel or skin abrasion reduces stress and discomfort for patients.
    • Enables routine cognitive assessments without disrupting daily routines.

    Bring EEG to Contract Research Organizations (CROs)

    Clinical trials require consistent, reliable data across various sites and patient populations. Zeto provides an efficient solution for brain monitoring in research.

    Key Benefits:

    • Reliable, high-quality data collection.
    • Simplified workflows for research teams.
    • Compatible with diverse hair types and patient profiles.

    Bring EEG to Sports Arenas – Monitoring Athletes’ Brain Health

    Real-time brain monitoring can help protect athletes from long-term neurological damage by providing immediate insights during games.

    Key Benefits:

    • Portable systems for on-site brain health assessments.
    • Real-time data collection supports safer sports practices.
    • Reduces the risk of undiagnosed concussions.

    Breaking Boundaries in Brain Monitoring

    Zeto is making EEG more accessible than ever – bridging the gap between advanced technology and everyday care settings. Our innovation and commitment to accessibility empower practitioners and researchers to break new ground in brain health.

    Take the Next Step: Explore how Zeto can transform your approach to brain monitoring or collaborate with us to pioneer new applications.

    Whether it’s in hospitals, research labs, or unexpected places like music halls, Zeto’s EEG technology is reshaping the future of brain health and neuroscience.

    Interested in learning more about this topic?

    Stay tuned for upcoming articles. If you haven’t already, subscribe to our newsletter or follow us on LinkedIn. Interested in a demo? Click here to schedule yours now.

    Zeto, Inc., Secures $31 Million In Series B Funding To Redefine The Future Of EEG Brain Monitoring

    SANTA CLARA, Calif., Jan. 8, 2025 /PRNewswire/ — Zeto, Inc., a fast-growing medical technology company revolutionizing EEG diagnostics with its cutting-edge devices and AI-driven cloud platform, has announced the recent successful closing of a $31 million funding round.

    The funding round was led by MindWorks Global (MWG), a Michigan-based investment entity funded by visionary entrepreneur-investors with a track record of building multi-billion-dollar enterprises. MWG’s Founder, CEO and Lead Partner, Mike Williams, is an accomplished entrepreneur and investor known for his expertise in scaling companies across different industries, including achieving a $1.1 billion exit from his most recent venture. Mike Williams said, “Zeto’s vision and technology are truly transformative for the medical arena and beyond, and we are excited to leverage our expertise and network to help drive the company’s growth. The world of EEG is going to be transformed immensely in the upcoming years, and Zeto is going to be at the forefront of it. Brain health assessment will extend beyond traditional healthcare, and we’re excited to support Zeto in pioneering new frontiers. It’s an exciting day!”

    Aswin Gunasekar, Zeto’s Founder and CEO said, “Zeto has reached a pivotal milestone, earning a reputation for game-changing innovation and experiencing rapid adoption of our solutions by leading healthcare institutions across the U.S. Our management team has long aspired to collaborate with accomplished entrepreneur-investors who have successfully scaled companies to drive meaningful societal impact and significant revenue. We are excited to welcome MindWorks Global partners to our board of directors who bring not only capital but also invaluable expertise, extensive experience, and a powerful network. Our dedicated team is eager to embark on this exciting next chapter in our company’s journey.”

    Zeto is grateful for the steadfast support and continued investments from its prior investors over the years. This new funding will enable Zeto to expand its commercial and operational teams, drive further growth and strengthen ongoing research and development efforts.

    About Zeto, Inc.

    Zeto, Inc., an award-winning medical technology company, is at the forefront of advancing EEG brain monitoring and diagnostics in healthcare. Through its innovative wearable devices, Zeto makes brain monitoring accessible in diverse clinical settings, including the ICU, ED, hospitals, offices, and at home. Backed by a powerful cloud-based platform, Zeto delivers nationwide monitoring and interpretation services by neurologists, along with AI-driven notifications for conditions such as seizures and epilepsy. Looking ahead, Zeto plans to expand its capabilities to detect and manage conditions like depression, stroke and traumatic brain injury. Zeto’s EEG systems, which received FDA clearances in 2018 and 2024, are currently commercially available in the United States.

    To learn more about Zeto’s products, please visit: https://zeto-inc.com or email us at info@zetoinc.com.

    Source – PRNewswire